Lecture 13: Linkage disequilibrium: Case-control approaches

In the textbooks

• Sham: Sections 6.1-6.6
• Ott: Section 13.4
• Weir: pages 113-138, 244-254

Other references

• Jorde LB (1995) Linkage disequilibrium as a gene-mapping tool. Am J Hum Genet 56:11-14
• Lander ES, Schork NJ (1994) Genetic dissection of complex traits. Science 265:2037-2048
• DJ Schaid and SJ Jacobsen (1999) Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions. Am J Epidemiol 149:706-711
• BFJ Manly (1997) Randomization, bootstrap and Monte Carlo methods in biology, 2nd edition. Chapman & Hall, London.