Lecture 11: Linkage analysis of quantitative traits in large families: Variance components methods

References

• L Almasy and J Blangero (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211
• CI Amos (1994) Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet 54:535-543
• DW Fulker and LR Cardon (1994) A sib-pair approach to interval mapping of quantitative trait loci. Am J Hum Genet 54:1092-1103
• DW Fulker, SS Cherny and LR Cardon (1995) Multipoint interval mapping of quantitative trait loci, using sib pairs. Am J Hum Genet 56:1224-1233