R/qtl2 QTL analysis for high-dimensional data and complex crosses
R/qtl2 (aka qtl2) is a reimplementation of the QTL analysis software
R/qtl, to better handle high-dimensional data
and complex cross designs. It is split
into qtl2geno (for calculating
genotype probabilities, imputations, and genetic maps),
qtl2scan (for QTL genome scans and
related calculations), and
qtl2plot (for data visualization).
A further package, qtl2convert,
contains functions for converting data among the R/qtl2,
and R/qtl formats, for example to convert genotype
probabilities produced by DOQTL to the format needed by qtl2scan, or
to convert qtl2scan results to the format produced by
R/qtl, so that they may be graphed with the R/qtl functions.
We’re considering revising many of the central data structures in R/qtl2. There is much that is useful here, but many of the details are likely to change.
R/qtl2 is early in development and so is not yet available on CRAN.
You can install R/qtl2 from GitHub.
install.packages(c("devtools", "yaml", "jsonlite", "data.table", "RcppEigen"))
Then, install R/qtl2 using
library(devtools) install_github(paste0("rqtl/qtl2", c("geno", "scan", "plot", "convert")))
- user guide
- input file formats (also see the sample data files and the qtl2data repository)
- differences between R/qtl and R/qtl2
- developer guide
- HMM benchmarks
- linear regression benchmarks
The qtl2geno, qtl2scan, and qtl2plot packages are free software; you can redistribute them and/or modify them under the terms of the GNU General Public License, version 3, as published by the Free Software Foundation.
These programs are distributed in the hope that they will be useful, but without any warranty; without even the implied warranty of merchantability or fitness for a particular purpose. See the GNU General Public License for more details.
A copy of the GNU General Public License, version 3, is available at http://www.r-project.org/Licenses/GPL-3
Sources on github: